Cargando…

Neonatal cardiac dysfunction and transcriptome changes caused by the absence of Celf1

The RNA binding protein Celf1 regulates alternative splicing in the nucleus and mRNA stability and translation in the cytoplasm. Celf1 is strongly down-regulated during mouse postnatal heart development. Its re-induction in adults induced severe heart failure and reversion to fetal splicing and gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Giudice, Jimena, Xia, Zheng, Li, Wei, Cooper, Thomas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069560/ https://www.ncbi.nlm.nih.gov/pubmed/27759042 http://dx.doi.org/10.1038/srep35550

Ejemplares similares

Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins
por: Wang, Eric T., et al.
Publicado: (2015)

Identification of CELF splicing activation and repression domains in vivo
por: Han, Jin, et al.
Publicado: (2005)

Repression of nuclear CELF activity can rescue CELF-regulated alternative splicing defects in skeletal muscle models of myotonic dystrophy
por: Berger, Dara S., et al.
Publicado: (2012)

Celf1 Is Required for Formation of Endoderm-Derived Organs in Zebrafish
por: Tahara, Naoyuki, et al.
Publicado: (2013)

Altered CELF1 binding to target transcripts in malignant T cells
por: Bohjanen, Paul R., et al.
Publicado: (2015)

High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology
por: Siddam, Archana D., et al.
Publicado: (2023)

Role of CELF2 in ferroptosis: Potential targets for cancer therapy (Review)
por: Li, Jiahao, et al.
Publicado: (2023)

Association of CELF2 polymorphism and the prognosis of nasopharyngeal carcinoma in southern Chinese population
por: Guo, Yun-Miao, et al.
Publicado: (2015)

CELF1 is Up-Regulated in Glioma and Promotes Glioma Cell Proliferation by Suppression of CDKN1B
por: Xia, Liang, et al.
Publicado: (2015)

CELF2 regulates the species-specific alternative splicing of TREM2
por: Yanaizu, Motoaki, et al.
Publicado: (2020)

Caenorhabditis elegans ETR-1/CELF has broad effects on the muscle cell transcriptome, including genes that regulate translation and neuroblast migration
por: Ochs, Matthew E., et al.
Publicado: (2022)

CELF1 is Up-Regulated in Glioma and Promotes Glioma Cell Proliferation by Suppression of CDKN1B: Erratum
por: Xia, Liang, et al.
Publicado: (2023)

Interleukin-10 control of pre-miR155 maturation involves CELF2
por: Yoon, Jeff S. J., et al.
Publicado: (2020)

Identification of CELF1 RNA targets by CLIP-seq in human HeLa cells
por: Le Tonquèze, Olivier, et al.
Publicado: (2016)

CELF1 is a central node in post-transcriptional regulatory programmes underlying EMT
por: Chaudhury, Arindam, et al.
Publicado: (2016)

Alzheimer’s Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci
por: Karch, Celeste M., et al.
Publicado: (2016)

Changes in the cuff pressure in neonates in the absence of nitrous oxide
por: Saracoglu, Ayten, et al.
Publicado: (2022)

Cardiac Remodeling in the Absence of Cardiac Contractile Dysfunction Is Sufficient to Promote Cancer Progression
por: Awwad, Lama, et al.
Publicado: (2022)

MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1
por: Kino, Yoshihiro, et al.
Publicado: (2009)

Structural insights into the targeting of mRNA GU-rich elements by the three RRMs of CELF1
por: Edwards, John M., et al.
Publicado: (2013)

Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1
por: Ishizuka, Akira, et al.
Publicado: (2014)

CELF1 promotes matrix metalloproteinases gene expression at transcriptional level in lens epithelial cells
por: Xiao, Jun, et al.
Publicado: (2022)

A Case of Neonatal Lupus Presenting with Myocardial Dysfunction in the Absence of Congenital Heart Block (CHB): Clinical Management and Brief Literature Review of Neonatal Cardiac Lupus
por: Jain, Samhita, et al.
Publicado: (2022)

Ancient antagonism between CELF and RBFOX families tunes mRNA splicing outcomes
por: Gazzara, Matthew R., et al.
Publicado: (2017)

CELF1 represses Doublesex1 expression via its 5’ UTR in the crustacean Daphnia magna
por: Tirta, Yusrifar Kharisma, et al.
Publicado: (2022)

Inactivation of the Celf1 Gene that Encodes an RNA-Binding Protein Delays the First Wave of Spermatogenesis in Mice
por: Cibois, Marie, et al.
Publicado: (2012)

Si-RNA mediated knockdown of CELF1 gene suppressed the proliferation of human lung cancer cells
por: Wu, Li-Na, et al.
Publicado: (2013)

Small molecule targeting CELF1 RNA-binding activity to control HSC activation and liver fibrosis
por: Tan, Yang, et al.
Publicado: (2022)

The cause of cardiac dysfunction
por: Horejs, Christine
Publicado: (2021)

Position-dependent activity of CELF2 in the regulation of splicing and implications for signal-responsive regulation in T cells
por: Ajith, Sandya, et al.
Publicado: (2016)

CELF Family Proteins in Cancer: Highlights on the RNA-Binding Protein/Noncoding RNA Regulatory Axis
por: Nasiri-Aghdam, Maryam, et al.
Publicado: (2021)

Celf4 controls mRNA translation underlying synaptic development in the prenatal mammalian neocortex
por: Salamon, Iva, et al.
Publicado: (2023)

RNA-binding protein CELF6 is cell cycle regulated and controls cancer cell proliferation by stabilizing p21
por: Liu, Gang, et al.
Publicado: (2019)

CELF RNA binding proteins promote axon regeneration in C. elegans and mammals through alternative splicing of Syntaxins
por: Chen, Lizhen, et al.
Publicado: (2016)

Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1
por: Cifdaloz, Metehan, et al.
Publicado: (2017)

RNA-binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1
por: Zhou, Limin, et al.
Publicado: (2022)

RNA-binding protein CELF2 inhibits breast cancer cell invasion and angiogenesis by downregulating NFATc1
por: Zhou, Limin, et al.
Publicado: (2021)

Distribution of alternative untranslated regions within the mRNA of the CELF1 splicing factor affects its expression
por: Kajdasz, Arkadiusz, et al.
Publicado: (2022)

Supplementary choline attenuates olive oil lipid emulsion‐induced enterocyte apoptosis through suppression of CELF1/AIF pathway
por: Yan, Jun‐Kai, et al.
Publicado: (2017)

Identification of Targets of CUG-BP, Elav-Like Family Member 1 (CELF1) Regulation in Embryonic Heart Muscle
por: Blech-Hermoni, Yotam, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_boaboskq11mfodacelkjbdadqf