(99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis

Technetium‐99m aprotinin was prepared from an optimised radiolabelling kit formulation containing aprotinin, alkaline buffer and stannous chloride (reducing agent) and radiolabelled using (99m)Tc‐pertechnetate. The labelling was achieved within 25 min, with radiochemical purities of >98%.

Detalles Bibliográficos
Autores principales: Denholt, Charlotte, Gillings, Nic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Short Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069565/
https://www.ncbi.nlm.nih.gov/pubmed/26923297
http://dx.doi.org/10.1002/jlcr.3381
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author Denholt, Charlotte
Gillings, Nic
author_facet Denholt, Charlotte
Gillings, Nic
author_sort Denholt, Charlotte
collection PubMed
description Technetium‐99m aprotinin was prepared from an optimised radiolabelling kit formulation containing aprotinin, alkaline buffer and stannous chloride (reducing agent) and radiolabelled using (99m)Tc‐pertechnetate. The labelling was achieved within 25 min, with radiochemical purities of >98%.
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spelling pubmed-50695652016-11-01 (99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis Denholt, Charlotte Gillings, Nic J Labelled Comp Radiopharm Short Note Technetium‐99m aprotinin was prepared from an optimised radiolabelling kit formulation containing aprotinin, alkaline buffer and stannous chloride (reducing agent) and radiolabelled using (99m)Tc‐pertechnetate. The labelling was achieved within 25 min, with radiochemical purities of >98%. John Wiley and Sons Inc. 2016-02-28 2016-04 /pmc/articles/PMC5069565/ /pubmed/26923297 http://dx.doi.org/10.1002/jlcr.3381 Text en Copyright © 2016 The Authors. Journal of Labelled Compounds and Radiopharmaceuticals published by John Wiley & Sons, Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Short Note
Denholt, Charlotte
Gillings, Nic
(99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
title (99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
title_full (99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
title_fullStr (99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
title_full_unstemmed (99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
title_short (99m)Tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
title_sort (99m)tc‐aprotinin – optimisation and validation of radiolabelling kits for routine preparation for diagnostic imaging of amyloidosis
topic Short Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069565/
https://www.ncbi.nlm.nih.gov/pubmed/26923297
http://dx.doi.org/10.1002/jlcr.3381
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