Cargando…

Cytoplasmic proliferating cell nuclear antigen connects glycolysis and cell survival in acute myeloid leukemia

Cytosolic proliferating cell nuclear antigen (PCNA), a scaffolding protein involved in DNA replication, has been described as a key element in survival of mature neutrophil granulocytes, which are non-proliferating cells. Herein, we demonstrated an active export of PCNA involved in cell survival and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohayon, Delphine, De Chiara, Alessia, Chapuis, Nicolas, Candalh, Céline, Mocek, Julie, Ribeil, Jean-Antoine, Haddaoui, Lamya, Ifrah, Norbert, Hermine, Olivier, Bouillaud, Frédéric, Frachet, Philippe, Bouscary, Didier, Witko-Sarsat, Véronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069676/ https://www.ncbi.nlm.nih.gov/pubmed/27759041 http://dx.doi.org/10.1038/srep35561

Ejemplares similares

Proliferating cell nuclear antigen acts as a cytoplasmic platform controlling human neutrophil survival
por: Witko-Sarsat, Véronique, et al.
Publicado: (2010)

Targeting cytosolic proliferating cell nuclear antigen in neutrophil-dominated inflammation
por: Chiara, Alessia De, et al.
Publicado: (2012)

Proteinase 3 Interferes With C1q-Mediated Clearance of Apoptotic Cells
por: Tacnet-Delorme, Pascale, et al.
Publicado: (2018)

Correction: Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils
por: Ohayon, Delphine, et al.
Publicado: (2019)

Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils
por: Ohayon, Delphine, et al.
Publicado: (2019)

Immunomodulatory role of phagocyte-derived chloramines involving lymphocyte glutathione
por: Witko-Sarsat, Véronique, et al.
Publicado: (1993)

Harnessing Neutrophil Survival Mechanisms during Chronic Infection by Pseudomonas aeruginosa: Novel Therapeutic Targets to Dampen Inflammation in Cystic Fibrosis
por: Marteyn, Benoît S., et al.
Publicado: (2017)

From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells
por: Grignano, Eric, et al.
Publicado: (2020)

Neutrophil-derived Oxidants and Proteinases as Immunomodulatory Mediators in Inflammation
por: Witko-Sarsat, V., et al.
Publicado: (1994)

Reducing neutrophil exposure to oxygen allows their basal state maintenance
por: Injarabian, Louise, et al.
Publicado: (2021)

Inflammation and CFTR: might neutrophils be the key in cystic fibrosis?
por: Witko-Sarsat, V, et al.
Publicado: (1999)

Rationale for Targeting Deregulated Metabolic Pathways as a Therapeutic Strategy in Acute Myeloid Leukemia
por: Chapuis, Nicolas, et al.
Publicado: (2019)

NLRP3 Is Involved in Neutrophil Mobilization in Experimental Periodontitis
por: Cheat, Banndith, et al.
Publicado: (2022)

Myeloperoxidase Promoter Polymorphism −463G Is Associated With More Severe Clinical Expression of Cystic Fibrosis Pulmonary Disease
por: Reynolds, Wanda F., et al.
Publicado: (2006)

Acetylation accumulates PFKFB3 in cytoplasm to promote glycolysis and protects cells from cisplatin-induced apoptosis
por: Li, Fu-Long, et al.
Publicado: (2018)

Specific circulating neutrophils subsets are present in clinically stable adults with cystic fibrosis and are further modulated by pulmonary exacerbations
por: Martin, Clémence, et al.
Publicado: (2022)

The compound packaged in virions is the key to trigger host glycolysis machinery for virus life cycle in the cytoplasm
por: Zhang, Siyuan, et al.
Publicado: (2020)

Neurotrophins are expressed in giant cell arteritis lesions and may contribute to vascular remodeling
por: Ly, Kim Heang, et al.
Publicado: (2014)

Targeting glutamine uptake in AML
por: Jacque, Nathalie, et al.
Publicado: (2014)

Interest of colchicine for the treatment of cystic fibrosis patients. Preliminary report.
por: Sermet-Gaudelus, I, et al.
Publicado: (1999)

Genetic Evidence for a Link Between Glycolysis and DNA Replication
por: Jannière, Laurent, et al.
Publicado: (2007)

The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing
por: Tesori, Valentina, et al.
Publicado: (2015)

GLYCOLYSIS IN RAT PERITONEAL MAST CELLS
por: Chakravarty, Nirmal
Publicado: (1965)

APR-246 induces early cell death by ferroptosis in acute myeloid leukemia
por: Birsen, Rudy, et al.
Publicado: (2021)

Compartmentalization of membrane trafficking, glucose transport, glycolysis, actin, tubulin and the proteasome in the cytoplasmic droplet/Hermes body of epididymal sperm
por: Au, Catherine E., et al.
Publicado: (2015)

Caspase Activation Is Required for Terminal Erythroid Differentiation
por: Zermati, Yael, et al.
Publicado: (2001)

Use of H(2)O(2) to Cause Oxidative Stress, the Catalase Issue
por: Ransy, Céline, et al.
Publicado: (2020)

Micromanaging aerobic respiration and glycolysis in cancer cells
por: Orang, Ayla V., et al.
Publicado: (2019)

Glycolysis in Innate Immune Cells Contributes to Autoimmunity
por: Xu, Yue, et al.
Publicado: (2022)

Antileukemic activity of the VPS34-IN1 inhibitor in acute myeloid leukemia
por: Meunier, Godelieve, et al.
Publicado: (2020)

Ineffective Erythropoiesis in β-Thalassemia
por: Ribeil, Jean-Antoine, et al.
Publicado: (2013)

Cytoplasmic Synthesis in Nerve Cells
por: Causey, G., et al.
Publicado: (1955)

Flow Cytometric Quantification of All Phases of the Cell Cycle and Apoptosis in a Two-Color Fluorescence Plot
por: Vignon, Christine, et al.
Publicado: (2013)

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
por: Takahashi, Akiko, et al.
Publicado: (2018)

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
por: Kishore, Madhav, et al.
Publicado: (2017)

Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
por: Kishore, Madhav, et al.
Publicado: (2018)

Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus
por: Rincheval, Vincent, et al.
Publicado: (2017)

Sulfide Oxidation Evidences the Immediate Cellular Response to a Decrease in the Mitochondrial ATP/O(2) Ratio
por: Bouillaud, Frédéric
Publicado: (2022)

Inhibition of Succinate Dehydrogenase by Pesticides (SDHIs) and Energy Metabolism
por: Bouillaud, Frederic
Publicado: (2023)

Dual cytoplasmic and nuclear localization of HTLV-1-encoded HBZ protein is a unique feature of adult T-cell leukemia
por: Forlani, Greta, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ks7kb2euv775ao97f810nk99dv