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TGF-β induces p53/Smads complex formation in the PAI-1 promoter to activate transcription

Transforming growth factor β (TGF-β) signaling facilitates tumor development during the advanced stages of tumorigenesis, but induces cell-cycle arrest for tumor suppression during the early stages. However, the mechanism of functional switching of TGF-β is still unknown, and it is unclear whether i...

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Detalles Bibliográficos
Autores principales:	Kawarada, Yuki, Inoue, Yasumichi, Kawasaki, Fumihiro, Fukuura, Keishi, Sato, Koichi, Tanaka, Takahito, Itoh, Yuka, Hayashi, Hidetoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069723/ https://www.ncbi.nlm.nih.gov/pubmed/27759037 http://dx.doi.org/10.1038/srep35483

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