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Integrins are not essential for entry of coxsackievirus A9 into SW480 human colon adenocarcinoma cells

BACKGROUND: Coxsackievirus A9 (CV-A9) is a pathogenic enterovirus type within the family Picornaviridae. CV-A9 infects A549 human epithelial lung carcinoma cells by attaching to the αVβ6 integrin receptor through a highly conserved Arg-Gly-Asp (RGD) motif, which is located at the exposed carboxy-ter...

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Detalles Bibliográficos
Autores principales: Heikkilä, Outi, Merilahti, Pirjo, Hakanen, Marika, Karelehto, Eveliina, Alanko, Jonna, Sukki, Maria, Kiljunen, Saija, Susi, Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069866/
https://www.ncbi.nlm.nih.gov/pubmed/27756316
http://dx.doi.org/10.1186/s12985-016-0619-y

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