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TransComb: genome-guided transcriptome assembly via combing junctions in splicing graphs
Transcriptome assemblers aim to reconstruct full-length transcripts from RNA-seq data. We present TransComb, a genome-guided assembler developed based on a junction graph, weighted by a bin-packing strategy and paired-end information. A newly designed extension method based on weighted junction grap...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069867/ https://www.ncbi.nlm.nih.gov/pubmed/27760567 http://dx.doi.org/10.1186/s13059-016-1074-1 |