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High-throughput assessment of context-dependent effects of chromatin proteins

BACKGROUND: Chromatin proteins control gene activity in a concerted manner. We developed a high-throughput assay to study the effects of the local chromatin environment on the regulatory activity of a protein of interest. The assay combines a previously reported multiplexing strategy based on barcod...

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Detalles Bibliográficos
Autores principales: Brueckner, Laura, van Arensbergen, Joris, Akhtar, Waseem, Pagie, Ludo, van Steensel, Bas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069885/
https://www.ncbi.nlm.nih.gov/pubmed/27777628
http://dx.doi.org/10.1186/s13072-016-0096-y

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