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A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T–Hg(2+)–T mismatched DNA

We report herein the use of an exonuclease III and G-quadruplex probe to construct a G-quadruplex-based luminescence detection platform for Hg(2+). Unlike common DNA-based Hg(2+) detection methods, when using the dsDNA probe to monitor the hairpin formation, the intercalation of the dsDNA probe may...

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Detalles Bibliográficos
Autores principales: Wang, Wanhe, Kang, Tian-Shu, Chan, Philip Wai Hong, Lu, Jin-Jian, Chen, Xiu-Ping, Leung, Chung-Hang, Ma, Dik-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069990/
https://www.ncbi.nlm.nih.gov/pubmed/27877846
http://dx.doi.org/10.1088/1468-6996/16/6/065004