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A label-free G-quadruplex-based mercury detection assay employing the exonuclease III-mediated cleavage of T–Hg(2+)–T mismatched DNA
We report herein the use of an exonuclease III and G-quadruplex probe to construct a G-quadruplex-based luminescence detection platform for Hg(2+). Unlike common DNA-based Hg(2+) detection methods, when using the dsDNA probe to monitor the hairpin formation, the intercalation of the dsDNA probe may...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5069990/ https://www.ncbi.nlm.nih.gov/pubmed/27877846 http://dx.doi.org/10.1088/1468-6996/16/6/065004 |