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Synaptic and cellular changes induced by the schizophrenia susceptibility gene G72 are rescued by N-acetylcysteine treatment

Genetic studies have linked the primate-specific gene locus G72 to the development of schizophrenia and bipolar disorder. Transgenic mice carrying the entire gene locus express G72 mRNA in dentate gyrus (DG) and entorhinal cortex, causing altered electrophysiological properties of their connections....

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Detalles Bibliográficos
Autores principales: Pósfai, B, Cserép, C, Hegedüs, P, Szabadits, E, Otte, D M, Zimmer, A, Watanabe, M, Freund, T F, Nyiri, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070069/
https://www.ncbi.nlm.nih.gov/pubmed/27163208
http://dx.doi.org/10.1038/tp.2016.74