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Life-threatening colitis and complete response with ipilimumab in a patient with metastatic BRAF-mutant melanoma and rheumatoid arthritis

Immune checkpoint inhibitors, such as ipilimumab (an anti-CTLA4 antibody), have become a commonly used therapy in cancer. To date, safety data of patients with underlying autoimmune disease is limited. We present a case of a patient with rheumatoid arthritis who was diagnosed of a BRAF-mutant metast...

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Detalles Bibliográficos
Autores principales: Aya, Francisco, Gaba, Lydia, Victoria, Ivan, Fernandez-Martinez, Aranzazu, Ruiz-Esquide, Virginia, Pineda, Estela, Tosca, Monica, Viladot, Margarita, Pereira, Veronica, Malvehy, Josep, Prat, Aleix, Arance, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070207/
https://www.ncbi.nlm.nih.gov/pubmed/27843587
http://dx.doi.org/10.1136/esmoopen-2015-000032