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Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?

BACKGROUND: Permanent renal dysfunction is considered as being a serious complication which may occur after major surgery and which furthermore may lead to increased morbidity and mortality. The objective of this study was to analyze the incidence of long-term postoperative renal dysfunction after p...

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Autores principales: Hassan, Basim Kamil, Dessau, Ram Benny Christian, Sahlström, Arne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070215/
https://www.ncbi.nlm.nih.gov/pubmed/27756352
http://dx.doi.org/10.1186/s13018-016-0457-z
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author Hassan, Basim Kamil
Dessau, Ram Benny Christian
Sahlström, Arne
author_facet Hassan, Basim Kamil
Dessau, Ram Benny Christian
Sahlström, Arne
author_sort Hassan, Basim Kamil
collection PubMed
description BACKGROUND: Permanent renal dysfunction is considered as being a serious complication which may occur after major surgery and which furthermore may lead to increased morbidity and mortality. The objective of this study was to analyze the incidence of long-term postoperative renal dysfunction after primary total hip and knee joint replacements. METHODS: Long-term postoperative renal dysfunction was analyzed in a retrospective study of 1301 consecutive primary total hip and knee joint replacements performed between January 2009 and December 2013. According to the RIFLE criteria, increased serum creatinine was an indicative of postoperative renal injury. The highest serum creatinine during the first postoperative week was chosen as a sign for maximum acute renal injury and was compared to the highest serum creatinine during the following 4–12 months. RESULTS: One hundred and forty two patients with an increase in postoperative serum creatinine were included in the follow-up study. Six patients (4.2 %) died due to non-renal causes during the follow-up period. One patient died of severe renal injury, which was relatively very early postoperatively, and another patient had a rise in serum creatinine to 316 μmol/l during the follow-up period. All the remaining 132 patients (94 %) had full recovery with serum creatinine which returned to preoperative levels. CONCLUSIONS: This study did not confirm that patients who underwent primary total hip and knee joint replacement surgery were at risk of developing permanent renal dysfunction up to 1 year after the index surgery.
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spelling pubmed-50702152016-10-24 Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements? Hassan, Basim Kamil Dessau, Ram Benny Christian Sahlström, Arne J Orthop Surg Res Research Article BACKGROUND: Permanent renal dysfunction is considered as being a serious complication which may occur after major surgery and which furthermore may lead to increased morbidity and mortality. The objective of this study was to analyze the incidence of long-term postoperative renal dysfunction after primary total hip and knee joint replacements. METHODS: Long-term postoperative renal dysfunction was analyzed in a retrospective study of 1301 consecutive primary total hip and knee joint replacements performed between January 2009 and December 2013. According to the RIFLE criteria, increased serum creatinine was an indicative of postoperative renal injury. The highest serum creatinine during the first postoperative week was chosen as a sign for maximum acute renal injury and was compared to the highest serum creatinine during the following 4–12 months. RESULTS: One hundred and forty two patients with an increase in postoperative serum creatinine were included in the follow-up study. Six patients (4.2 %) died due to non-renal causes during the follow-up period. One patient died of severe renal injury, which was relatively very early postoperatively, and another patient had a rise in serum creatinine to 316 μmol/l during the follow-up period. All the remaining 132 patients (94 %) had full recovery with serum creatinine which returned to preoperative levels. CONCLUSIONS: This study did not confirm that patients who underwent primary total hip and knee joint replacement surgery were at risk of developing permanent renal dysfunction up to 1 year after the index surgery. BioMed Central 2016-10-19 /pmc/articles/PMC5070215/ /pubmed/27756352 http://dx.doi.org/10.1186/s13018-016-0457-z Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Hassan, Basim Kamil
Dessau, Ram Benny Christian
Sahlström, Arne
Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?
title Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?
title_full Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?
title_fullStr Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?
title_full_unstemmed Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?
title_short Is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?
title_sort is there a risk of permanent renal dysfunction after primary total hip and knee joint replacements?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070215/
https://www.ncbi.nlm.nih.gov/pubmed/27756352
http://dx.doi.org/10.1186/s13018-016-0457-z
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