Cargando…
ASCO highlights podcast: head and neck cancers
A critical review of the head and neck cancer research highlights of the American Society of Clinical Oncology (ASCO) meeting 2016, held in June 2016 in Chicago, is presented in this podcast. Considering the most interesting and practice-changing trials reported at the meeting, the key trial compari...
Autor principal: | |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070245/ https://www.ncbi.nlm.nih.gov/pubmed/27843642 http://dx.doi.org/10.1136/esmoopen-2016-000099 |
_version_ | 1782461105544626176 |
---|---|
author | Merlano, Marco |
author_facet | Merlano, Marco |
author_sort | Merlano, Marco |
collection | PubMed |
description | A critical review of the head and neck cancer research highlights of the American Society of Clinical Oncology (ASCO) meeting 2016, held in June 2016 in Chicago, is presented in this podcast. Considering the most interesting and practice-changing trials reported at the meeting, the key trial comparing gemcitabine plus cisplatin against 5-FU (5-fluorouracil) plus cisplatin in the treatment of nasopharyngeal carcinoma is highlighted. The GORTEC2007-02 trial comparing induction docetaxel/platinum/5-FU followed by cetuximab-radiotherapy against concurrent chemo-radiotherapy for N2b/c-N3 non operated stage III-IV squamous cell cancer of the head and neck is also discussed. An overview of the research reported using immunotherapy in head and neck cancer is also given, considering maturing data and particularly in relapsing patients, where response rates, though low, are better than with current therapies, and the responses are long lasting. Future developments are also considered, again with a focus on immunotherapy, but also considering combination with radiotherapy and chemoradiation. |
format | Online Article Text |
id | pubmed-5070245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-50702452016-11-14 ASCO highlights podcast: head and neck cancers Merlano, Marco ESMO Open Podcast A critical review of the head and neck cancer research highlights of the American Society of Clinical Oncology (ASCO) meeting 2016, held in June 2016 in Chicago, is presented in this podcast. Considering the most interesting and practice-changing trials reported at the meeting, the key trial comparing gemcitabine plus cisplatin against 5-FU (5-fluorouracil) plus cisplatin in the treatment of nasopharyngeal carcinoma is highlighted. The GORTEC2007-02 trial comparing induction docetaxel/platinum/5-FU followed by cetuximab-radiotherapy against concurrent chemo-radiotherapy for N2b/c-N3 non operated stage III-IV squamous cell cancer of the head and neck is also discussed. An overview of the research reported using immunotherapy in head and neck cancer is also given, considering maturing data and particularly in relapsing patients, where response rates, though low, are better than with current therapies, and the responses are long lasting. Future developments are also considered, again with a focus on immunotherapy, but also considering combination with radiotherapy and chemoradiation. BMJ Publishing Group 2016-09-05 /pmc/articles/PMC5070245/ /pubmed/27843642 http://dx.doi.org/10.1136/esmoopen-2016-000099 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
spellingShingle | Podcast Merlano, Marco ASCO highlights podcast: head and neck cancers |
title | ASCO highlights podcast: head and neck cancers |
title_full | ASCO highlights podcast: head and neck cancers |
title_fullStr | ASCO highlights podcast: head and neck cancers |
title_full_unstemmed | ASCO highlights podcast: head and neck cancers |
title_short | ASCO highlights podcast: head and neck cancers |
title_sort | asco highlights podcast: head and neck cancers |
topic | Podcast |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070245/ https://www.ncbi.nlm.nih.gov/pubmed/27843642 http://dx.doi.org/10.1136/esmoopen-2016-000099 |
work_keys_str_mv | AT merlanomarco ascohighlightspodcastheadandneckcancers |