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ASCO highlights podcast: head and neck cancers

A critical review of the head and neck cancer research highlights of the American Society of Clinical Oncology (ASCO) meeting 2016, held in June 2016 in Chicago, is presented in this podcast. Considering the most interesting and practice-changing trials reported at the meeting, the key trial compari...

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Autor principal: Merlano, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070245/
https://www.ncbi.nlm.nih.gov/pubmed/27843642
http://dx.doi.org/10.1136/esmoopen-2016-000099
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author Merlano, Marco
author_facet Merlano, Marco
author_sort Merlano, Marco
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description A critical review of the head and neck cancer research highlights of the American Society of Clinical Oncology (ASCO) meeting 2016, held in June 2016 in Chicago, is presented in this podcast. Considering the most interesting and practice-changing trials reported at the meeting, the key trial comparing gemcitabine plus cisplatin against 5-FU (5-fluorouracil) plus cisplatin in the treatment of nasopharyngeal carcinoma is highlighted. The GORTEC2007-02 trial comparing induction docetaxel/platinum/5-FU followed by cetuximab-radiotherapy against concurrent chemo-radiotherapy for N2b/c-N3 non operated stage III-IV squamous cell cancer of the head and neck is also discussed. An overview of the research reported using immunotherapy in head and neck cancer is also given, considering maturing data and particularly in relapsing patients, where response rates, though low, are better than with current therapies, and the responses are long lasting. Future developments are also considered, again with a focus on immunotherapy, but also considering combination with radiotherapy and chemoradiation.
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spelling pubmed-50702452016-11-14 ASCO highlights podcast: head and neck cancers Merlano, Marco ESMO Open Podcast A critical review of the head and neck cancer research highlights of the American Society of Clinical Oncology (ASCO) meeting 2016, held in June 2016 in Chicago, is presented in this podcast. Considering the most interesting and practice-changing trials reported at the meeting, the key trial comparing gemcitabine plus cisplatin against 5-FU (5-fluorouracil) plus cisplatin in the treatment of nasopharyngeal carcinoma is highlighted. The GORTEC2007-02 trial comparing induction docetaxel/platinum/5-FU followed by cetuximab-radiotherapy against concurrent chemo-radiotherapy for N2b/c-N3 non operated stage III-IV squamous cell cancer of the head and neck is also discussed. An overview of the research reported using immunotherapy in head and neck cancer is also given, considering maturing data and particularly in relapsing patients, where response rates, though low, are better than with current therapies, and the responses are long lasting. Future developments are also considered, again with a focus on immunotherapy, but also considering combination with radiotherapy and chemoradiation. BMJ Publishing Group 2016-09-05 /pmc/articles/PMC5070245/ /pubmed/27843642 http://dx.doi.org/10.1136/esmoopen-2016-000099 Text en Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/ This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Podcast
Merlano, Marco
ASCO highlights podcast: head and neck cancers
title ASCO highlights podcast: head and neck cancers
title_full ASCO highlights podcast: head and neck cancers
title_fullStr ASCO highlights podcast: head and neck cancers
title_full_unstemmed ASCO highlights podcast: head and neck cancers
title_short ASCO highlights podcast: head and neck cancers
title_sort asco highlights podcast: head and neck cancers
topic Podcast
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070245/
https://www.ncbi.nlm.nih.gov/pubmed/27843642
http://dx.doi.org/10.1136/esmoopen-2016-000099
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