NTRK gene fusions as novel targets of cancer therapy across multiple tumour types

The tropomyosin receptor kinase (Trk) receptor family comprises 3 transmembrane proteins referred to as Trk A, B and C (TrkA, TrkB and TrkC) receptors that are encoded by the NTRK1, NTRK2 and NTRK3 genes, respectively. These receptor tyrosine kinases are expressed in human neuronal tissue and play a...

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Detalles Bibliográficos
Autores principales: Amatu, Alessio, Sartore-Bianchi, Andrea, Siena, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070277/
https://www.ncbi.nlm.nih.gov/pubmed/27843590
http://dx.doi.org/10.1136/esmoopen-2015-000023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070277/
https://www.ncbi.nlm.nih.gov/pubmed/27843590
http://dx.doi.org/10.1136/esmoopen-2015-000023

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