Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis

Somatic mutations of KIT are frequently found in mastocytosis and gastrointestinal stromal tumor (GIST), while germline mutations of KIT are rare, and only found in few cases of familial GIST and mastocytosis. Although ligand-independent activation is the common feature of KIT mutations, the phenoty...

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Detalles Bibliográficos
Autores principales: Ke, Hengning, Kazi, Julhash U., Zhao, Hui, Sun, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070372/
https://www.ncbi.nlm.nih.gov/pubmed/27777718
http://dx.doi.org/10.1186/s13578-016-0120-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070372/
https://www.ncbi.nlm.nih.gov/pubmed/27777718
http://dx.doi.org/10.1186/s13578-016-0120-8

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