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Germline mutations of KIT in gastrointestinal stromal tumor (GIST) and mastocytosis
Somatic mutations of KIT are frequently found in mastocytosis and gastrointestinal stromal tumor (GIST), while germline mutations of KIT are rare, and only found in few cases of familial GIST and mastocytosis. Although ligand-independent activation is the common feature of KIT mutations, the phenoty...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070372/ https://www.ncbi.nlm.nih.gov/pubmed/27777718 http://dx.doi.org/10.1186/s13578-016-0120-8 |