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Further structure–activity relationships study of substituted dithiolethiones as glutathione-inducing neuroprotective agents
BACKGROUND: Parkinson’s disease is a neurodegenerative disorder associated with oxidative stress and glutathione depletion. The induction of cellular glutathione levels by exogenous molecules is a promising neuroprotective approach to limit the oxidative damage that characterizes Parkinson’s disease...
Autores principales: | Brown, Dennis A., Betharia, Swati, Yen, Jui-Hung, Kuo, Ping-Chang, Mistry, Hitesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070379/ https://www.ncbi.nlm.nih.gov/pubmed/27812368 http://dx.doi.org/10.1186/s13065-016-0210-z |
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