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Further structure–activity relationships study of substituted dithiolethiones as glutathione-inducing neuroprotective agents

BACKGROUND: Parkinson’s disease is a neurodegenerative disorder associated with oxidative stress and glutathione depletion. The induction of cellular glutathione levels by exogenous molecules is a promising neuroprotective approach to limit the oxidative damage that characterizes Parkinson’s disease...

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Detalles Bibliográficos
Autores principales: Brown, Dennis A., Betharia, Swati, Yen, Jui-Hung, Kuo, Ping-Chang, Mistry, Hitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070379/
https://www.ncbi.nlm.nih.gov/pubmed/27812368
http://dx.doi.org/10.1186/s13065-016-0210-z

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