Genetic Screening and Analysis of LKB1 Gene in Chinese Patients with Peutz-Jeghers Syndrome

BACKGROUND: Peutz-Jeghers syndrome (PJS) is an autosomal dominant genetic disease. It severely decreases patient quality of life and leads elevated cancer risk. Germline mutation of LKB1 is the leading cause of familial PJS. MATERIAL/METHODS: To characterize the germline mutation of LKB1 gene in Chi...

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Detalles Bibliográficos
Autores principales: Chen, Chunyan, Zhang, Xiaomei, Wang, Deqiang, Wang, Fangyu, Pan, Jian, Wang, Zhenkai, Liu, Chang, Wu, Lin, Lu, Heng, Li, Nan, Wei, Juan, Shi, Hui, Wan, Haijun, Zhu, Ming, Chen, Senqing, Zhou, Yun, Zhou, Xin, Yang, Liu, Liu, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070620/
https://www.ncbi.nlm.nih.gov/pubmed/27721366
http://dx.doi.org/10.12659/MSM.897498

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