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What do we learn from the murine Jacob/Nsmf gene knockout for human disease?
Mutations in the NSMF gene have been related to Kallmann syndrome. Conflicting results have been reported on the subcellular localization of Jacob/NELF, the protein encoded by the NSMF gene. Some reports indicate an extracellular localization and a function as a guidance molecule for migration of Gn...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070631/ https://www.ncbi.nlm.nih.gov/pubmed/27803842 http://dx.doi.org/10.1080/21675511.2016.1241361 |