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Regulation of HIF-1α stability by lysine methylation

The level and activity of critical regulatory proteins in cells are tightly controlled by several tiers of post-translational modifications. HIF-1α is maintained at low levels under normoxia conditions by the collaboration between PHD proteins and the VHL-containing E3 ubiquitin ligase complex. We r...

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Detalles Bibliográficos
Autores principales:	Baek, Sung Hee, Kim, Keun Il
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2016
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070701/ https://www.ncbi.nlm.nih.gov/pubmed/26973343 http://dx.doi.org/10.5483/BMBRep.2016.49.5.053

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