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Fine-Tuning of the Kaposi’s Sarcoma-Associated Herpesvirus Life Cycle in Neighboring Cells through the RTA-JAG1-Notch Pathway

Kaposi’s sarcoma (KS)-associated herpesvirus (KSHV) is an oncogenic pathogen that displays latent and lytic life cycles. In KS lesions, infiltrated immune cells, secreted viral and/or cellular cytokines, and hypoxia orchestrate a chronic pro-lytic microenvironment that can promote KSHV reactivation....

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Detalles Bibliográficos
Autores principales:	Li, Shasha, Hu, Hao, He, Zhiheng, Liang, Deguang, Sun, Rui, Lan, Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070770/ https://www.ncbi.nlm.nih.gov/pubmed/27760204 http://dx.doi.org/10.1371/journal.ppat.1005900

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