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Testing Danegaptide Effects on Kidney Function after Ischemia/Reperfusion Injury in a New Porcine Two Week Model

INTRODUCTION: Ischemia/reperfusion injury (I/R-I) is a leading cause of acute kidney injury (AKI) and is associated with increased mortality. Danegaptide is a selective modifier of the gap junction protein connexion 43. It has cytoprotective as well as anti-arrhythmic properties and has been shown t...

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Detalles Bibliográficos
Autores principales: Amdisen, Chris, Keller, Anna K., Hansen, Rie Schultz, Nørregaard, Rikke, Krag, Søren Palmelund, Møldrup, Ulla, Pedersen, Michael, Jespersen, Bente, Birn, Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070773/
https://www.ncbi.nlm.nih.gov/pubmed/27760220
http://dx.doi.org/10.1371/journal.pone.0164109