Pristane-Accelerated Autoimmune Disease in (SWR X NZB) F1 Mice Leads to Prominent Tubulointerstitial Inflammation and Human Lupus Nephritis-Like Fibrosis

Mouse models lupus nephritis (LN) have provided important insights into disease pathogenesis, although none have been able to recapitulate all features of the human disease. Using comprehensive longitudinal analyses, we characterized a novel accelerated mouse model of lupus using pristane treatment...

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Detalles Bibliográficos
Autores principales: Gardet, Agnes, Chou, Wei C., Reynolds, Taylor L., Velez, Diana B., Fu, Kai, Czerkowicz, Julia M., Bajko, Jeffrey, Ranger, Ann M., Allaire, Normand, Kerns, Hannah M., Ryan, Sarah, Legault, Holly M., Dunstan, Robert W., Lafyatis, Robert, Lukashev, Matvey, Viney, Joanne L., Browning, Jeffrey L., Rabah, Dania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5070861/
https://www.ncbi.nlm.nih.gov/pubmed/27760209
http://dx.doi.org/10.1371/journal.pone.0164423

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