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Slitrk Missense Mutations Associated with Neuropsychiatric Disorders Distinctively Impair Slitrk Trafficking and Synapse Formation
Slit- and Trk-like (Slitrks) are a six-member family of synapse organizers that control excitatory and inhibitory synapse formation by forming trans-synaptic adhesions with LAR receptor protein tyrosine phosphatases (PTPs). Intriguingly, genetic mutations of Slitrks have been associated with a multi...
Autores principales: | Kang, Hyeyeon, Han, Kyung Ah, Won, Seoung Youn, Kim, Ho Min, Lee, Young-Ho, Ko, Jaewon, Um, Ji Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071332/ https://www.ncbi.nlm.nih.gov/pubmed/27812321 http://dx.doi.org/10.3389/fnmol.2016.00104 |
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