Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata

Two new phenylpropanoid glycosides named cuneataside E (1) and cuneataside F (2), were isolated from the aerial parts of Lespedeza cuneata (Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (...

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Detalles Bibliográficos
Autores principales: Zhang, Chuangfeng, Zhou, Jian, Yang, Jingzhi, Li, Chuangjun, Ma, Jie, Zhang, Dan, Zhang, Dongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071639/
https://www.ncbi.nlm.nih.gov/pubmed/27818923
http://dx.doi.org/10.1016/j.apsb.2016.05.009
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author Zhang, Chuangfeng
Zhou, Jian
Yang, Jingzhi
Li, Chuangjun
Ma, Jie
Zhang, Dan
Zhang, Dongming
author_facet Zhang, Chuangfeng
Zhou, Jian
Yang, Jingzhi
Li, Chuangjun
Ma, Jie
Zhang, Dan
Zhang, Dongming
author_sort Zhang, Chuangfeng
collection PubMed
description Two new phenylpropanoid glycosides named cuneataside E (1) and cuneataside F (2), were isolated from the aerial parts of Lespedeza cuneata (Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D NMR). In in vitro bioassays at 10 μmol/L, compound 1 showed moderate hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced toxicity in HeG2 cells.
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spelling pubmed-50716392016-11-04 Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata Zhang, Chuangfeng Zhou, Jian Yang, Jingzhi Li, Chuangjun Ma, Jie Zhang, Dan Zhang, Dongming Acta Pharm Sin B Original Article Two new phenylpropanoid glycosides named cuneataside E (1) and cuneataside F (2), were isolated from the aerial parts of Lespedeza cuneata (Dum. Cours.) G. Don, whose structures were E and Z isomer, respectively. Their structures were elucidated on the basis of comprehensive spectroscopic analysis (UV, IR, HR-ESI-MS, 1D and 2D NMR). In in vitro bioassays at 10 μmol/L, compound 1 showed moderate hepatoprotective activity against N-acetyl-p-aminophenol (APAP)-induced toxicity in HeG2 cells. Elsevier 2016-11 2016-06-17 /pmc/articles/PMC5071639/ /pubmed/27818923 http://dx.doi.org/10.1016/j.apsb.2016.05.009 Text en © 2016 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Zhang, Chuangfeng
Zhou, Jian
Yang, Jingzhi
Li, Chuangjun
Ma, Jie
Zhang, Dan
Zhang, Dongming
Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_full Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_fullStr Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_full_unstemmed Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_short Two new phenylpropanoid glycosides from the aerial parts of Lespedeza cuneata
title_sort two new phenylpropanoid glycosides from the aerial parts of lespedeza cuneata
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071639/
https://www.ncbi.nlm.nih.gov/pubmed/27818923
http://dx.doi.org/10.1016/j.apsb.2016.05.009
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