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Hog1p activation by marasmic acid through inhibition of the histidine kinase Sln1p

BACKGROUND: The histidine kinase (HK) MoHik1p within the high‐osmolarity glycerol (HOG) pathway is known to be the target of the fungicide fludioxonil. Treatment of the fungus with fludioxonil causes an uncontrolled hyperactivation of the pathway and cell death. In this study, we used a target‐based...

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Detalles Bibliográficos
Autores principales: Jacob, Stefan, Schüffler, Anja, Thines, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071701/
https://www.ncbi.nlm.nih.gov/pubmed/26888741
http://dx.doi.org/10.1002/ps.4257

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