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PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers

INTRODUCTION: HIV epidemics in the Asia-Pacific region are concentrated among men who have sex with men (MSM) and other key populations. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention intervention and could be a potential game changer in the region. We discuss the progress towards Pr...

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Autores principales: Zablotska, Iryna, Grulich, Andrew E, Phanuphak, Nittaya, Anand, Tarandeep, Janyam, Surang, Poonkasetwattana, Midnight, Baggaley, Rachel, van Griensven, Frits, Lo, Ying-Ru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071746/
https://www.ncbi.nlm.nih.gov/pubmed/27760688
http://dx.doi.org/10.7448/IAS.19.7.21119
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author Zablotska, Iryna
Grulich, Andrew E
Phanuphak, Nittaya
Anand, Tarandeep
Janyam, Surang
Poonkasetwattana, Midnight
Baggaley, Rachel
van Griensven, Frits
Lo, Ying-Ru
author_facet Zablotska, Iryna
Grulich, Andrew E
Phanuphak, Nittaya
Anand, Tarandeep
Janyam, Surang
Poonkasetwattana, Midnight
Baggaley, Rachel
van Griensven, Frits
Lo, Ying-Ru
author_sort Zablotska, Iryna
collection PubMed
description INTRODUCTION: HIV epidemics in the Asia-Pacific region are concentrated among men who have sex with men (MSM) and other key populations. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention intervention and could be a potential game changer in the region. We discuss the progress towards PrEP implementation in the Asia-Pacific region, including opportunities and barriers. DISCUSSION: Awareness about PrEP in the Asia-Pacific is still low and so are its levels of use. A high proportion of MSM who are aware of PrEP are willing to use it. Key PrEP implementation barriers include poor knowledge about PrEP, limited access to PrEP, weak or non-existent HIV prevention programmes for MSM and other key populations, high cost of PrEP, stigma and discrimination against key populations and restrictive laws in some countries. Only several clinical trials, demonstration projects and a few larger-scale implementation studies have been implemented so far in Thailand and Australia. However, novel approaches to PrEP implementation have emerged: researcher-, facility- and community-led models of care, with PrEP services for fee and for free. The WHO consolidated guidelines on HIV testing, treatment and prevention call for an expanded access to PrEP worldwide and have provided guidance on PrEP implementation in the region. Some countries like Australia have released national PrEP guidelines. There are growing community leadership and consultation processes to initiate PrEP implementation in Asia and the Pacific. CONCLUSIONS: Countries of the Asia-Pacific region will benefit from adding PrEP to their HIV prevention packages, but for many this is a critical step that requires resourcing. Having an impact on the HIV epidemic requires investment. The next years should see the region transitioning from limited PrEP implementation projects to growing access to PrEP and expansion of HIV prevention programmes.
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spelling pubmed-50717462016-10-27 PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers Zablotska, Iryna Grulich, Andrew E Phanuphak, Nittaya Anand, Tarandeep Janyam, Surang Poonkasetwattana, Midnight Baggaley, Rachel van Griensven, Frits Lo, Ying-Ru J Int AIDS Soc Commentary INTRODUCTION: HIV epidemics in the Asia-Pacific region are concentrated among men who have sex with men (MSM) and other key populations. Pre-exposure prophylaxis (PrEP) is an effective HIV prevention intervention and could be a potential game changer in the region. We discuss the progress towards PrEP implementation in the Asia-Pacific region, including opportunities and barriers. DISCUSSION: Awareness about PrEP in the Asia-Pacific is still low and so are its levels of use. A high proportion of MSM who are aware of PrEP are willing to use it. Key PrEP implementation barriers include poor knowledge about PrEP, limited access to PrEP, weak or non-existent HIV prevention programmes for MSM and other key populations, high cost of PrEP, stigma and discrimination against key populations and restrictive laws in some countries. Only several clinical trials, demonstration projects and a few larger-scale implementation studies have been implemented so far in Thailand and Australia. However, novel approaches to PrEP implementation have emerged: researcher-, facility- and community-led models of care, with PrEP services for fee and for free. The WHO consolidated guidelines on HIV testing, treatment and prevention call for an expanded access to PrEP worldwide and have provided guidance on PrEP implementation in the region. Some countries like Australia have released national PrEP guidelines. There are growing community leadership and consultation processes to initiate PrEP implementation in Asia and the Pacific. CONCLUSIONS: Countries of the Asia-Pacific region will benefit from adding PrEP to their HIV prevention packages, but for many this is a critical step that requires resourcing. Having an impact on the HIV epidemic requires investment. The next years should see the region transitioning from limited PrEP implementation projects to growing access to PrEP and expansion of HIV prevention programmes. International AIDS Society 2016-10-18 /pmc/articles/PMC5071746/ /pubmed/27760688 http://dx.doi.org/10.7448/IAS.19.7.21119 Text en © 2016 World Health Organization; licensee IAS http://creativecommons.org/licenses/by/3.0/igo/legalcode This is an open access article distributed under the terms of the Creative Commons Attribution IGO License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted.
spellingShingle Commentary
Zablotska, Iryna
Grulich, Andrew E
Phanuphak, Nittaya
Anand, Tarandeep
Janyam, Surang
Poonkasetwattana, Midnight
Baggaley, Rachel
van Griensven, Frits
Lo, Ying-Ru
PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers
title PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers
title_full PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers
title_fullStr PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers
title_full_unstemmed PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers
title_short PrEP implementation in the Asia-Pacific region: opportunities, implementation and barriers
title_sort prep implementation in the asia-pacific region: opportunities, implementation and barriers
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071746/
https://www.ncbi.nlm.nih.gov/pubmed/27760688
http://dx.doi.org/10.7448/IAS.19.7.21119
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