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AKT/GSK3β signaling pathway is critically involved in human pluripotent stem cell survival
Human embryonic and induced pluripotent stem cells are self-renewing pluripotent stem cells (PSC) that can differentiate into a wide range of specialized cells. Basic fibroblast growth factor is essential for PSC survival, stemness and self-renewal. PI3K/AKT pathway regulates cell viability and apop...
Autores principales: | Romorini, Leonardo, Garate, Ximena, Neiman, Gabriel, Luzzani, Carlos, Furmento, Verónica Alejandra, Guberman, Alejandra Sonia, Sevlever, Gustavo Emilio, Scassa, María Elida, Miriuka, Santiago Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071844/ https://www.ncbi.nlm.nih.gov/pubmed/27762303 http://dx.doi.org/10.1038/srep35660 |
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