Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation

To enhance the surface bioactivity of titanium (Ti) prostheses, an electroactive polyvinylidene fluoride (PVDF) film was prepared on a Ti substrate to provide a mimetic of the electrical microenvironment, which facilitated the performance of cell functions. The results of cell proliferation and diff...

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Detalles Bibliográficos
Autores principales: Zhou, Zhengnan, Li, Weiping, He, Tianrui, Qian, Lei, Tan, Guoxin, Ning, Chengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071852/
https://www.ncbi.nlm.nih.gov/pubmed/27762318
http://dx.doi.org/10.1038/srep35512
Descripción
Sumario:To enhance the surface bioactivity of titanium (Ti) prostheses, an electroactive polyvinylidene fluoride (PVDF) film was prepared on a Ti substrate to provide a mimetic of the electrical microenvironment, which facilitated the performance of cell functions. The results of cell proliferation and differentiation assays indicated that polarization of the PVDF-Ti (PTi) altered its surface charge, thus inducing adhesion, proliferation and osteogenic differentiation of cells. The polarized PVDF-Ti (PPTi) may therefore find applications in bone regeneration.

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