Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation

To enhance the surface bioactivity of titanium (Ti) prostheses, an electroactive polyvinylidene fluoride (PVDF) film was prepared on a Ti substrate to provide a mimetic of the electrical microenvironment, which facilitated the performance of cell functions. The results of cell proliferation and diff...

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Detalles Bibliográficos
Autores principales: Zhou, Zhengnan, Li, Weiping, He, Tianrui, Qian, Lei, Tan, Guoxin, Ning, Chengyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071852/
https://www.ncbi.nlm.nih.gov/pubmed/27762318
http://dx.doi.org/10.1038/srep35512
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author Zhou, Zhengnan
Li, Weiping
He, Tianrui
Qian, Lei
Tan, Guoxin
Ning, Chengyun
author_facet Zhou, Zhengnan
Li, Weiping
He, Tianrui
Qian, Lei
Tan, Guoxin
Ning, Chengyun
author_sort Zhou, Zhengnan
collection PubMed
description To enhance the surface bioactivity of titanium (Ti) prostheses, an electroactive polyvinylidene fluoride (PVDF) film was prepared on a Ti substrate to provide a mimetic of the electrical microenvironment, which facilitated the performance of cell functions. The results of cell proliferation and differentiation assays indicated that polarization of the PVDF-Ti (PTi) altered its surface charge, thus inducing adhesion, proliferation and osteogenic differentiation of cells. The polarized PVDF-Ti (PPTi) may therefore find applications in bone regeneration.
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spelling pubmed-50718522016-10-26 Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation Zhou, Zhengnan Li, Weiping He, Tianrui Qian, Lei Tan, Guoxin Ning, Chengyun Sci Rep Article To enhance the surface bioactivity of titanium (Ti) prostheses, an electroactive polyvinylidene fluoride (PVDF) film was prepared on a Ti substrate to provide a mimetic of the electrical microenvironment, which facilitated the performance of cell functions. The results of cell proliferation and differentiation assays indicated that polarization of the PVDF-Ti (PTi) altered its surface charge, thus inducing adhesion, proliferation and osteogenic differentiation of cells. The polarized PVDF-Ti (PPTi) may therefore find applications in bone regeneration. Nature Publishing Group 2016-10-20 /pmc/articles/PMC5071852/ /pubmed/27762318 http://dx.doi.org/10.1038/srep35512 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zhou, Zhengnan
Li, Weiping
He, Tianrui
Qian, Lei
Tan, Guoxin
Ning, Chengyun
Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation
title Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation
title_full Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation
title_fullStr Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation
title_full_unstemmed Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation
title_short Polarization of an electroactive functional film on titanium for inducing osteogenic differentiation
title_sort polarization of an electroactive functional film on titanium for inducing osteogenic differentiation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071852/
https://www.ncbi.nlm.nih.gov/pubmed/27762318
http://dx.doi.org/10.1038/srep35512
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AT qianlei polarizationofanelectroactivefunctionalfilmontitaniumforinducingosteogenicdifferentiation
AT tanguoxin polarizationofanelectroactivefunctionalfilmontitaniumforinducingosteogenicdifferentiation
AT ningchengyun polarizationofanelectroactivefunctionalfilmontitaniumforinducingosteogenicdifferentiation

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