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Interferon Regulatory Factor 4 controls T(H1) cell effector function and metabolism

The transcription factor Interferon Regulatory Factor 4 (IRF4) is essential for T(H2) and T(H17) cell formation and controls peripheral CD8(+) T cell differentiation. We used Listeria monocytogenes infection to characterize the function of IRF4 in T(H1) responses. IRF4(−/−) mice generated only margi...

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Detalles Bibliográficos
Autores principales:	Mahnke, Justus, Schumacher, Valéa, Ahrens, Stefanie, Käding, Nadja, Feldhoff, Lea Marie, Huber, Magdalena, Rupp, Jan, Raczkowski, Friederike, Mittrücker, Hans-Willi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071867/ https://www.ncbi.nlm.nih.gov/pubmed/27762344 http://dx.doi.org/10.1038/srep35521

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