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Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1
Matrix metalloproteinases (MMPs) are a family of secreted endopeptidases expressed by neurons and glia. Regulated MMP activity contributes to physiological synaptic plasticity, while dysregulated activity can stimulate injury. Disentangling the role individual MMPs play in synaptic plasticity is dif...
Autores principales: | Allen, Megan, Ghosh, Suhasini, Ahern, Gerard P., Villapol, Sonia, Maguire-Zeiss, Kathleen A., Conant, Katherine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071868/ https://www.ncbi.nlm.nih.gov/pubmed/27762280 http://dx.doi.org/10.1038/srep35497 |
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