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Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1

Matrix metalloproteinases (MMPs) are a family of secreted endopeptidases expressed by neurons and glia. Regulated MMP activity contributes to physiological synaptic plasticity, while dysregulated activity can stimulate injury. Disentangling the role individual MMPs play in synaptic plasticity is dif...

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Detalles Bibliográficos
Autores principales: Allen, Megan, Ghosh, Suhasini, Ahern, Gerard P., Villapol, Sonia, Maguire-Zeiss, Kathleen A., Conant, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071868/
https://www.ncbi.nlm.nih.gov/pubmed/27762280
http://dx.doi.org/10.1038/srep35497

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