Metformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis

Resistance towards chemotherapy is a common complication in treatment of oral cancers, which leads to treatment failure and poor outcome. In recent years, a growing body of evidence has shown that tumour hypoxia significantly contributes to chemoresistance. Metformin, a widely used oral hypoglycaemi...

Descripción completa

Detalles Bibliográficos
Autores principales: Qi, Xiaofeng, Xu, Wengguang, Xie, Junqi, Wang, Yufeng, Han, Shengwei, Wei, Zheng, Ni, Yanhong, Dong, Yingchun, Han, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5071902/
https://www.ncbi.nlm.nih.gov/pubmed/27762347
http://dx.doi.org/10.1038/srep35788

Ejemplares similares

Ejemplares similares