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Comparison of monocyte human leukocyte antigen-DR expression and stimulated tumor necrosis factor alpha production as outcome predictors in severe sepsis: a prospective observational study

BACKGROUND: Identifying patients in the immunosuppressive phase of sepsis is essential for development of immunomodulatory therapies. Little data exists comparing the ability of the two most well-studied markers of sepsis-induced immunosuppression, human leukocyte antigen (HLA)-DR expression and lip...

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Detalles Bibliográficos
Autores principales: Drewry, Anne M., Ablordeppey, Enyo A., Murray, Ellen T., Beiter, Evan R., Walton, Andrew H., Hall, Mark W., Hotchkiss, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072304/
https://www.ncbi.nlm.nih.gov/pubmed/27760554
http://dx.doi.org/10.1186/s13054-016-1505-0