Loss of Mgat5a-mediated N-glycosylation stimulates regeneration in zebrafish

BACKGROUND: We are using genetics to identify genes specifically involved in hearing regeneration. In a large-scale genetic screening, we identified mgat5a, a gene in the N-glycosylation biosynthesis pathway whose activity negatively impacts hair cell regeneration. METHODS: We used a combination of...

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Detalles Bibliográficos
Autores principales: Pei, Wuhong, Huang, Sunny C., Xu, Lisha, Pettie, Kade, Ceci, María Laura, Sánchez, Mario, Allende, Miguel L., Burgess, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072312/
https://www.ncbi.nlm.nih.gov/pubmed/27795824
http://dx.doi.org/10.1186/s13619-016-0031-5

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