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Targeting Epithelial-Mesenchymal Transition for Identification of Inhibitors for Pancreatic Cancer Cell Invasion and Tumor Spheres Formation

BACKGROUND: Pancreatic cancer has an enrichment of stem-like cancer cells (CSCs) that contribute to chemoresistant tumors prone to metastasis and recurrence. Drug screening assays based on cytotoxicity cannot identify specific CSC inhibitors, because CSCs comprise only a small portion of cancer cell...

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Detalles Bibliográficos
Autores principales:	Polireddy, Kishore, Dong, Ruochen, McDonald, Peter R., Wang, Tao, Luke, Brendan, Chen, Ping, Broward, Melinda, Roy, Anuradha, Chen, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072586/ https://www.ncbi.nlm.nih.gov/pubmed/27764163 http://dx.doi.org/10.1371/journal.pone.0164811

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