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Immunohistochemistry Successfully Uncovers Intratumoral Heterogeneity and Widespread Co-Losses of Chromatin Regulators in Clear Cell Renal Cell Carcinoma

Recent studies have shown that intratumoral heterogeneity (ITH) is prevalent in clear cell renal cell carcinoma (ccRCC), based on DNA sequencing and chromosome aberration analysis of multiple regions from the same tumor. VHL mutations were found to be universal throughout individual tumors when it o...

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Detalles Bibliográficos
Autores principales:	Jiang, Wei, Dulaimi, Essel, Devarajan, Karthik, Parsons, Theodore, Wang, Qiong, Liao, Lili, Cho, Eun-Ah, O'Neill, Raymond, Solomides, Charalambos, Peiper, Stephen C., Testa, Joseph R., Uzzo, Robert, Yang, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072613/ https://www.ncbi.nlm.nih.gov/pubmed/27764136 http://dx.doi.org/10.1371/journal.pone.0164554

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