Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses

Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic fever. The virus is endemic in over 120 countries, causing over 350 million infections per year. Dengue vaccine development is challenging because of the need to induce simultaneous protection against four antigenicall...

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Detalles Bibliográficos
Autores principales: Metz, Stefan W., Tian, Shaomin, Hoekstra, Gabriel, Yi, Xianwen, Stone, Michelle, Horvath, Katie, Miley, Michael J., DeSimone, Joseph, Luft, Chris J., de Silva, Aravinda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072622/
https://www.ncbi.nlm.nih.gov/pubmed/27764114
http://dx.doi.org/10.1371/journal.pntd.0005071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072622/
https://www.ncbi.nlm.nih.gov/pubmed/27764114
http://dx.doi.org/10.1371/journal.pntd.0005071

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