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Precisely Molded Nanoparticle Displaying DENV-E Proteins Induces Robust Serotype-Specific Neutralizing Antibody Responses
Dengue virus (DENV) is the causative agent of dengue fever and dengue hemorrhagic fever. The virus is endemic in over 120 countries, causing over 350 million infections per year. Dengue vaccine development is challenging because of the need to induce simultaneous protection against four antigenicall...
Autores principales: | Metz, Stefan W., Tian, Shaomin, Hoekstra, Gabriel, Yi, Xianwen, Stone, Michelle, Horvath, Katie, Miley, Michael J., DeSimone, Joseph, Luft, Chris J., de Silva, Aravinda M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072622/ https://www.ncbi.nlm.nih.gov/pubmed/27764114 http://dx.doi.org/10.1371/journal.pntd.0005071 |
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