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Substance P Promotes the Proliferation, but Inhibits Differentiation and Mineralization of Osteoblasts from Rats with Spinal Cord Injury via RANKL/OPG System
Spinal cord injury (SCI) causes a significant amount of bone loss, which results in osteoporosis (OP). The neuropeptide substance P (SP) and SP receptors may play important roles in the pathogenesis of OP after SCI. To identify the roles of SP in the bone marrow mesenchymal stem cell derived osteobl...
Autores principales: | Liu, Hai-Juan, Yan, Hua, Yan, Jun, Li, Hao, Chen, Liang, Han, Li-Ren, Yang, Xiao-Fei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072631/ https://www.ncbi.nlm.nih.gov/pubmed/27764190 http://dx.doi.org/10.1371/journal.pone.0165063 |
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