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Non-Canonical EZH2 Transcriptionally Activates RelB in Triple Negative Breast Cancer
Enhancer of zeste homology 2 (EZH2) is the methyltransferase component of the polycomb repressive complex (PRC2) which represses gene transcription via histone H3 trimethylation at lysine 23 (H3K27me3). EZH2 activity has been linked with oncogenesis where it is thought to block expression of certain...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072726/ https://www.ncbi.nlm.nih.gov/pubmed/27764181 http://dx.doi.org/10.1371/journal.pone.0165005 |