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Differential Dynamics of CALR Mutant Allele Burden in Myeloproliferative Neoplasms during Interferon Alfa Treatment

Discovery of somatic mutations in the calreticulin gene (CALR) has identified a subgroup of Philadelphia-negative chronic myeloproliferative neoplasms (MPN) with separate haematological characteristics and prognosis. CALR mutations serve as novel markers both of diagnostic value and as targets for m...

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Detalles Bibliográficos
Autores principales:	Kjær, Lasse, Cordua, Sabrina, Holmström, Morten O., Thomassen, Mads, Kruse, Torben A, Pallisgaard, Niels, Larsen, Thomas S., de Stricker, Karin, Skov, Vibe, Hasselbalch, Hans C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072743/ https://www.ncbi.nlm.nih.gov/pubmed/27764253 http://dx.doi.org/10.1371/journal.pone.0165336

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