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Polymyositis anti-SRP antibodies and pregnancy about 2 cases

Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations...

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Detalles Bibliográficos
Autores principales: Ousmane, Cissé, Makhtar, Ba El Hadji, Fatoumata, Ba, Massi, Gams Daniel, Lémine, Daddah Sami Mouhamed, Soda, Diop-Sène Marieme, Dieynaba, Sow Adjaratou, Anna, Basse, Bouna, Seck Lala, Moustapha, Ndiaye, Gallo, Diop Amadou, Mansour, Ndiaye Mouhamadou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072849/
https://www.ncbi.nlm.nih.gov/pubmed/27795789
http://dx.doi.org/10.11604/pamj.2016.24.192.9690
Descripción
Sumario:Anti-SRP myopathy represents 4 to 6% of all the inflammatory myopathies. It has been described since the 80s and its influence on pregnancy and vice versa has been highlighted recently. We report two cases of anti-SRP myopathy associated with pregnancy. In the first case, the initial manifestations of the disease started in post partum and the second case was an anti-SRP myopathy patient before pregnancy. In both cases we objectified outbreaks during post-partum. Pregnancy seems to promote outbreaks. The inactive myopathy seems to presents no serious maternal-fetal complications as well as the usual dose of corticosteroids. The treatment (corticosteroid) during pregnancy is indicated given the risk of worsening during the post-partum.