Concurrent Kimura disease and lupus nephritis: A case report

BACKGROUND: Kimura disease is a rare chronic inflammatory disorder with peripheral eosinophilia and elevated serum IgE and is also frequently complicated by nephropathy. METHODS: We report a rare case of Kimura disease concomitant with lupus nephritis in a 72-year old male patient with recurrent une...

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Detalles Bibliográficos
Autores principales: Wang, Haitao, Fang, Fang, Sun, Ying, Wang, Songlan, Mao, Yonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2016
Materias:
4000
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5072951/
https://www.ncbi.nlm.nih.gov/pubmed/27741124
http://dx.doi.org/10.1097/MD.0000000000005086
Descripción
Sumario:BACKGROUND: Kimura disease is a rare chronic inflammatory disorder with peripheral eosinophilia and elevated serum IgE and is also frequently complicated by nephropathy. METHODS: We report a rare case of Kimura disease concomitant with lupus nephritis in a 72-year old male patient with recurrent unexplained lymphadenopathy, renal lesions, and immunologic abnormalities. RESULTS: The patient was successfully managed with gamma immunoglobulin, intravenous pulse methylprednisolone therapy, hydroxychloroquine, and prednisone. CONCLUSION: This is the first report of a case of Kimura disease concomitant with lupus nephritis and highlights the importance of considering lupus nephritis as a possible concurrent disease in patients with Kimura disease that have immunologic abnormalities.

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