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In vitro potency, in vitro and in vivo efficacy of liposomal alendronate in combination with γδ T cell immunotherapy in mice

Nitrogen-containing bisphosphonates (N-BP), including zoledronic acid (ZOL) and alendronate (ALD), have been proposed as sensitisers in γδ T cell immunotherapy in pre-clinical and clinical studies. Therapeutic efficacy of N-BPs is hampered by their rapid renal excretion and high affinity for bone. L...

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Detalles Bibliográficos
Autores principales:	Hodgins, Naomi O., Al-Jamal, Wafa' T., Wang, Julie T-W., Parente-Pereira, Ana C., Liu, Mao, Maher, John, Al-Jamal, Khuloud T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Publishers 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073077/ https://www.ncbi.nlm.nih.gov/pubmed/27664328 http://dx.doi.org/10.1016/j.jconrel.2016.09.023

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