Cargando…

Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance

Cognitive functioning can be differentially modulated by components of the immune system. Interferon-γ (IFNγ) is a pro-inflammatory cytokine whose production is altered in many conditions displaying some degree of cognitive deficits, although its role in cognitive functioning is still unclear. Here...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monteiro, S, Ferreira, F M, Pinto, V, Roque, S, Morais, M, de Sá-Calçada, D, Mota, C, Correia-Neves, M, Cerqueira, J J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073154/ https://www.ncbi.nlm.nih.gov/pubmed/26731444 http://dx.doi.org/10.1038/tp.2015.194

Ejemplares similares

IFNγ and iNOS-Mediated Alterations in the Bone Marrow and Thymus and Its Impact on Mycobacterium avium-Induced Thymic Atrophy
por: Barreira-Silva, Palmira, et al.
Publicado: (2021)

An Efficient Chronic Unpredictable Stress Protocol to Induce Stress-Related Responses in C57BL/6 Mice
por: Monteiro, Susana, et al.
Publicado: (2015)

Chronic Mycobacterium avium infection differentially affects the cytokine expression profile of three mouse strains, but has no effect on behavior
por: Roque, Susana, et al.
Publicado: (2023)

Exploring Female Mice Interstrain Differences Relevant for Models of Depression
por: de Sá-Calçada, Daniela, et al.
Publicado: (2015)

Absence of IFNγ expression induces neuronal degeneration in the spinal cord of adult mice
por: Victório, Sheila CS, et al.
Publicado: (2010)

Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4
por: Gomez, Andrea M, et al.
Publicado: (2014)

Coordinate induction of IFN-α and -γ by SARS-CoV also in the absence of virus replication
por: Castilletti, Concetta, et al.
Publicado: (2005)

Enrichment of IFN-γ producing cells in different murine adipose tissue depots upon infection with an apicomplexan parasite
por: Teixeira, Luzia, et al.
Publicado: (2016)

Type I IFN Inhibits Alternative Macrophage Activation during Mycobacterium tuberculosis Infection and Leads to Enhanced Protection in the Absence of IFN-γ Signaling
por: Moreira-Teixeira, Lúcia, et al.
Publicado: (2016)

T-Bet independent development of IFNγ secreting natural T helper 1 cell population in the absence of Itk
por: Kannan, Arun K., et al.
Publicado: (2017)

CD45RA, CD8β, and IFNγ Are Potential Immune Biomarkers of Human Cognitive Function
por: Esgalhado, André J., et al.
Publicado: (2020)

Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity
por: Krisnawati, Dyah Ika, et al.
Publicado: (2019)

Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
por: He, Tingyan, et al.
Publicado: (2023)

IFNα and IFNγ Impede Marek’s Disease Progression
por: Bertzbach, Luca D., et al.
Publicado: (2019)

Compensatory Hippocampal Neurogenesis in the Absence of Cognitive Impairment Following Experimental Hippocampectomy in Adult Rats
por: Cardoso, Giuliana T. M., et al.
Publicado: (2021)

IFN-γ Mediates the Rejection of Haematopoietic Stem Cells in IFN-γR1-Deficient Hosts
por: Rottman, Martin, et al.
Publicado: (2008)

IFN-γ modulates Ly-49 receptors on NK cells in IFN-γ-induced pregnancy failure
por: Li, Zhong-Yin, et al.
Publicado: (2015)

Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling
por: Apriamashvili, Georgi, et al.
Publicado: (2022)

Cloning, expression and immunoassay detection of ferret IFN-γ
por: Ochi, Atsuo, et al.
Publicado: (2008)

Multifactorial Remodeling of the Cancer Immunopeptidome by IFNγ
por: Newey, Alice, et al.
Publicado: (2023)

Biologic functions of the IFN‐γ receptors
por: Tau, G., et al.
Publicado: (2001)

IFN-γ, should not be ignored in SLE
por: Liu, Wenping, et al.
Publicado: (2022)

Ubiquitin ligase TRIM3 controls hippocampal plasticity and learning by regulating synaptic γ-actin levels
por: Schreiber, Joerg, et al.
Publicado: (2015)

Pulmonary IFN-γ Causes Lymphocytic Inflammation and Cough Hypersensitivity by Increasing the Number of IFN-γ-Secreting T Lymphocytes
por: Deng, Zheng, et al.
Publicado: (2022)

The Effects of Stress on Hippocampal Neurogenesis and Behavior in the Absence of Lipocalin-2
por: Ferreira, Ana Catarina, et al.
Publicado: (2023)

Host autophagy limits Toxoplasma gondii proliferation in the absence of IFN-γ by affecting the hijack of Rab11A-positive vesicles
por: Pan, Lingtao, et al.
Publicado: (2022)

Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice
por: Guo, Yujun, et al.
Publicado: (2021)

Bidirectional crosstalk between epithelial–mesenchymal plasticity and IFNγ-induced PD-L1 expression promotes tumour progression
por: Burger, Gerhard A., et al.
Publicado: (2022)

Epigenetic Activation and Silencing of the Gene that Encodes IFN-γ
por: Aune, Thomas M., et al.
Publicado: (2013)

Lack of Interleukin-6 Affects IFN-γ and TNF-α Production and Early In Vivo Control of Brucella abortus Infection
por: Guimarães, Erika S., et al.
Publicado: (2020)

Immunoproteasome Assembly: Cooperative Incorporation of Interferon γ (IFN-γ)–inducible Subunits
por: Griffin, Thomas A., et al.
Publicado: (1998)

γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice
por: Rungratanawanich, Wiramon, et al.
Publicado: (2019)

Effect of interferon-γ (IFN-γ) on transforming growth factor-β (TGF-β) regulation of sialomucin complex/Muc4
por: Price-Schiavi, SA, et al.
Publicado: (2001)

IFNγ is a central node of cancer immune equilibrium
por: Walsh, Michael J., et al.
Publicado: (2023)

IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells
por: Coomes, Stephanie M., et al.
Publicado: (2015)

Bromodomain inhibitor JQ1 reversibly blocks IFN-γ production
por: Gibbons, Hunter R., et al.
Publicado: (2019)

Lipopolysaccharide induces IFN-γ production in human NK cells
por: Kanevskiy, Leonid M., et al.
Publicado: (2013)

Absence of IL-17A in Litomosoides sigmodontis-infected mice influences worm development and drives elevated filarial-specific IFN-γ
por: Ritter, Manuel, et al.
Publicado: (2018)

Plasticity of hippocampal memories in humans
por: Horner, Aidan J, et al.
Publicado: (2017)

Neuromodulation of Hippocampal-Prefrontal Cortical Synaptic Plasticity and Functional Connectivity: Implications for Neuropsychiatric Disorders
por: Ruggiero, Rafael Naime, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4kc6snq9pimo6nl4vkuh32jug1