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Negative role of TAK1 in marginal zone B-cell development incidental to NF-κB noncanonical pathway activation
The transcription factor nuclear factor-κB (NF-κB) signaling pathway is crucial in B-cell physiology. One key molecule regulating this pathway is the serine/threonine kinase TAK1 (MAP3K7). TAK1 is responsible for positive feedback mechanisms in B-cell receptor signaling that serve as an NF-κB activa...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073155/ https://www.ncbi.nlm.nih.gov/pubmed/27121163 http://dx.doi.org/10.1038/icb.2016.44 |