Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer

We report the draft genome sequence of Streptomyces sp. TP-A0874 isolated from compost. This strain produces catechoserine, a new catecholate-type inhibitor of tumor cell invasion. The genome harbors at least six gene clusters for polyketide and nonribosomal peptide biosyntheses. The biosynthetic ge...

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Detalles Bibliográficos
Autores principales: Komaki, Hisayuki, Hosoyama, Akira, Ichikawa, Natsuko, Igarashi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073265/
https://www.ncbi.nlm.nih.gov/pubmed/27795278
http://dx.doi.org/10.1128/genomeA.01163-16
Descripción
Sumario:We report the draft genome sequence of Streptomyces sp. TP-A0874 isolated from compost. This strain produces catechoserine, a new catecholate-type inhibitor of tumor cell invasion. The genome harbors at least six gene clusters for polyketide and nonribosomal peptide biosyntheses. The biosynthetic gene cluster for catechoserines was identified by bioinformatic analysis.

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