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Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer

We report the draft genome sequence of Streptomyces sp. TP-A0874 isolated from compost. This strain produces catechoserine, a new catecholate-type inhibitor of tumor cell invasion. The genome harbors at least six gene clusters for polyketide and nonribosomal peptide biosyntheses. The biosynthetic ge...

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Detalles Bibliográficos
Autores principales: Komaki, Hisayuki, Hosoyama, Akira, Ichikawa, Natsuko, Igarashi, Yasuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073265/
https://www.ncbi.nlm.nih.gov/pubmed/27795278
http://dx.doi.org/10.1128/genomeA.01163-16
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author Komaki, Hisayuki
Hosoyama, Akira
Ichikawa, Natsuko
Igarashi, Yasuhiro
author_facet Komaki, Hisayuki
Hosoyama, Akira
Ichikawa, Natsuko
Igarashi, Yasuhiro
author_sort Komaki, Hisayuki
collection PubMed
description We report the draft genome sequence of Streptomyces sp. TP-A0874 isolated from compost. This strain produces catechoserine, a new catecholate-type inhibitor of tumor cell invasion. The genome harbors at least six gene clusters for polyketide and nonribosomal peptide biosyntheses. The biosynthetic gene cluster for catechoserines was identified by bioinformatic analysis.
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spelling pubmed-50732652016-10-24 Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer Komaki, Hisayuki Hosoyama, Akira Ichikawa, Natsuko Igarashi, Yasuhiro Genome Announc Prokaryotes We report the draft genome sequence of Streptomyces sp. TP-A0874 isolated from compost. This strain produces catechoserine, a new catecholate-type inhibitor of tumor cell invasion. The genome harbors at least six gene clusters for polyketide and nonribosomal peptide biosyntheses. The biosynthetic gene cluster for catechoserines was identified by bioinformatic analysis. American Society for Microbiology 2016-10-20 /pmc/articles/PMC5073265/ /pubmed/27795278 http://dx.doi.org/10.1128/genomeA.01163-16 Text en Copyright © 2016 Komaki et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license (http://creativecommons.org/licenses/by/4.0/) .
spellingShingle Prokaryotes
Komaki, Hisayuki
Hosoyama, Akira
Ichikawa, Natsuko
Igarashi, Yasuhiro
Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer
title Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer
title_full Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer
title_fullStr Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer
title_full_unstemmed Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer
title_short Draft Genome Sequence of Streptomyces sp. TP-A0874, a Catechoserine Producer
title_sort draft genome sequence of streptomyces sp. tp-a0874, a catechoserine producer
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073265/
https://www.ncbi.nlm.nih.gov/pubmed/27795278
http://dx.doi.org/10.1128/genomeA.01163-16
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