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CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes

CD4(+) T cells are at the nexus of the innate and adaptive arms of the immune system. However, little is known about the evolutionary history of CD4(+) T cells, and it is unclear whether their differentiation into specialized subsets is conserved in early vertebrates. In this study, we have created...

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Detalles Bibliográficos
Autores principales: Dee, Christopher T., Nagaraju, Raghavendar T., Athanasiadis, Emmanouil I., Gray, Caroline, Fernandez del Ama, Laura, Johnston, Simon A., Secombes, Christopher J., Cvejic, Ana, Hurlstone, Adam F. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073357/
https://www.ncbi.nlm.nih.gov/pubmed/27694495
http://dx.doi.org/10.4049/jimmunol.1600959