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CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes
CD4(+) T cells are at the nexus of the innate and adaptive arms of the immune system. However, little is known about the evolutionary history of CD4(+) T cells, and it is unclear whether their differentiation into specialized subsets is conserved in early vertebrates. In this study, we have created...
Autores principales: | Dee, Christopher T., Nagaraju, Raghavendar T., Athanasiadis, Emmanouil I., Gray, Caroline, Fernandez del Ama, Laura, Johnston, Simon A., Secombes, Christopher J., Cvejic, Ana, Hurlstone, Adam F. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5073357/ https://www.ncbi.nlm.nih.gov/pubmed/27694495 http://dx.doi.org/10.4049/jimmunol.1600959 |
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